Cardioprotective effect of monophosphoryl lipid A is mediated by opening KATPchannels in rabbit heart
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چکیده
منابع مشابه
Delayed ischemic preconditioning is mediated by opening of ATP-sensitive potassium channels in the rabbit heart.
Cardioprotection from preconditioning reappears 24 h after the initial stimulus. This phenomenon is called the second window of protection (SWOP). We hypothesized that opening of the ATP-sensitive potassium (KATP) channel mediates the protective effect of SWOP. Rabbits were preconditioned (PC) with four cycles of 5-min regional ischemia each followed by 10 min of reperfusion. Twenty-four hours ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1996
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(96)81632-9